https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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2009, discovery of a fresh phenotype for bacteria in narrow nanofluidic slits; and initial detection of neighborhood protein buildings together DNA applying good-point out nanopores
It had been only during the 1990s although, when nanotechnology experienced Sophisticated to your level the place single molecules may be manipulated, that the first experimental units commenced to appear.
Multicolor imaging with the bacterial nucleoid and cell division proteins with blue, orange, and close to-infrared fluorescent proteins
Because 2000, Dekker has shifted the leading focus of his perform toward biophysics where he scientific studies the Qualities of solitary biomolecules and cells utilizing the applications of nanotechnology. This change of area was driven by his fascination for that extraordinary working of Organic molecular buildings, and from the extended-expression point of view that numerous interesting discoveries may be anticipated On this discipline.[five] Recent traces of exploration in his biophysics team are during the parts of:[six]
That could be a aspiration of mine and we set to work using a tasty dose of naivety. That is something which will most likely produce stunning ends in the more time expression, but that does not issue. You should not only want to work within the concerns of tomorrow, but additionally around the concerns in the day following tomorrow.’
Cornelis (Cees) Dekker (Haren, 7 april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
A lot of linked developments adopted, where by our team set up different transistor variants for instance solitary-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, https://www.ceesdekker.net and coupled various transistors into smaller proof-of-basic principle Digital circuits.
Dynamic ParB–DNA interactions initiate and preserve a partition condensate for bacterial chromosome segregation
‘Indeed, I understand men and women were being shocked at enough time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to admit that it experienced turn into a bit bored, I didn’t understand much any more. The sector went much more into the appliance facet, how you could integrate nanotubes into Digital circuits.
Resolving the stage dimension in condensin-driven DNA loop extrusion identifies ATP binding because the stage-generating procedure
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
2006, initial demonstration of molecular sorting in the lab with a chip utilizing biomotors; discovery of nanobubbles in sound-point out nanopores; and to start with estimate of electrokinetic Power conversion in the nanofluidic channel
Visualization of unstained DNA nanostructures with Sophisticated in-emphasis transmission electron microscopy approaches
Stable-state nanopores have verified for being a astonishingly adaptable probe for solitary-molecule Evaluation of DNA. I will describe some of our recent conclusions – precisely DNA knots – and our endeavours to extend the abilities of reliable-condition nanopores even more, within the path of one-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.